CD44 anticorps (APC)

N° du produit ABIN272367

Cet anticorps anti-CD44 est un anticorps Souris Monoclonal détectant CD44 dans FACS. Adapté pour Humain.

Aperçu rapide pour CD44 anticorps (APC) (ABIN272367)

Antigène: CD44

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: MEM-85

Détail du produit anti-CD44 anticorps (APC)

Specificité: The antibody MEM-85 reacts with both cell surface-expressed and soluble form of CD44 antigen (Phagocyte glycoprotein 1), a 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.), it is negative on platelets and hepatocytes.

Purification: Size-Exclusion Chromatography

Immunogène: Leukocytes of a patient suffering from LGL Type Leukaemia

Isotype: IgG2b

Information d'application

Indications d'application: Further Comments: HLDA IV, WS Code NL 706 HLDA VI, WS Code AS Ref.15

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline (PBS) containing 15 mM Sodium Azide and 0.2 % (w/v) high-grade protease free BSA as a stabilizing agent

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1

ID gène: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling